PReS-FINAL-1016: Micro vesicles as a magnifying glass; uncovering potential biomarkers in juvenile idiopathic arthritis

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PReS-FINAL-1016: Micro vesicles as a magnifying glass; uncovering potential biomarkers in juvenile idiopathic arthritis

Introduction Juvenile idiopathic arthritis (JIA) is a common chronic inflammatory diseases in childhood. Despite remission as a result of a plethora of treatment techniques, the chronic and relapsing nature of the disease requires continuous treatment which causes adverse side effects. It is important to uncover a biomarker that can efficiently predict patient responses to therapy as well as de...

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Introduction The outcome of children with juvenile idiopathic arthritis (JIA) has improved over the last decades. However, the disease course is still not easy to predict, especially based on traditional clinical factors. In the German prospective controlled observational multicentre study ICON-JIA (Inception Cohort Of Newly-diagnosed patients with JIA) patients with diagnosis of JIA <12 months...

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Results Our sample included 42 patients with juvenile idiopathic arthritis (JIA, mean age at evaluation 13.9 ± 7.9 years, mean disease duration was 6.9 ± 7.6 years, Male/Female ratio:10/32). Among them, 27 (64.3%) were oligoarthritis, 13 (30.9%) polyarthritis, 1 (2.4%) systemic arthritis and 1 (2.4%) psoriasic arthritis. Uveitis were present in 6 patients. Only 5 patients had clinical and labor...

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Introduction Juvenile idiopathic arthritis (JIA) is the most common rheumatologic disorder of childhood. It is a group of diseases characterized by chronic synovitis, associated with many extra-articular manifestations including pulmonary involvement, usually in the systemic type. Alterations of pulmonary function in JIA may be a complication of the underlying disease or related to treatment wi...

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ژورنال

عنوان ژورنال: Pediatric Rheumatology

سال: 2013

ISSN: 1546-0096

DOI: 10.1186/1546-0096-11-s2-p13